Leucocyte-derived bioactive substances in fresh frozen plasma

Fresh frozen plasma induced thrombocytopenia

Transfusions of blood products are common in medical practice and can be lifesaving in certain situations. Potentially life threatening reactions could occur and physicians should be alerted. Here we describe a case of thrombocytopenia that was induced by transfusion of fresh frozen plasma (FFP). A 52 years old male presented to the emergency department after two episodes of hematochezia that r...

Avoiding the misuse of fresh frozen plasma.

Coagulation Factors Level in Fresh Frozen Plasma in Rwanda.

UNLABELLED Objectives: To determine the level of coagulation factors and inherited inhibitors in Fresh Frozen Plasma (FFP) and to evaluate Prothrombin Time and activated partial thrombin time in fresh frozen plasma. DESIGN Cross-sectional study. SETTING Jomo Kenyatta University of Agriculture and Technology in Medical Laboratory Sciences. SUBJECTS Eighteen blood bags collected from volunt...

Fresh-frozen plasma use in a South African tertiary hospital.

Despite available guidelines on indications for fresh-frozen plasma (FFP) transfusion, inappropriate use is increasing worldwide. We evaluated FFP administration to patients admitted to the Steve Biko Academic Hospital over 4 months, including indications for use and completeness of requisition forms. Transfusions were considered inappropriate for 39.5% of units administered. Of request forms s...

APROTININ: EFFECTS ON BLOOD LOSS AND FRESH FROZEN PLASMA REQUIREMENT IN CARDIAC OPERATIONS

 ABSTRACT Background: Aprotinin has been used increasingly to reduce postoperative blood loss in open-heart operations due to the potentialities for complications and high cost, it would seem reasonable to use aprotinin more selectively in small doses in the prime solution of the pump. Methods: We prospectively studied the effect of preoperative low dose aprotinin [2 million units (230mg)] on b...